Diabetes mellitus is a disease in which the body does not produce or does not use insulin effectively. It is not simply hyperglycemia. Magnesium is involved in the interaction of more than 300 enzyme reactions in the body and is necessary for the transmission of nerve impulses, temperature regulation, detoxification, energy production, the formation of healthy bones and is vital for cardiovascular health. The incidence of insulin resistance and metabolic syndrome correlates with the availability of magnesium (Mg). Researchers showed that magnesium supplementation resulted in a significant improvement of fasting plasma glucose and some insulin sensitivity indices (ISIs) compared to placebo. The results provide significant evidence that oral Mg supplementation improves insulin sensitivity even in people with normal magnesium levels, overweight, and non-diabetic subjects. This study emphasizes the need for an early optimization of Mg status to prevent insulin resistance and subsequently type 2 diabetes.
